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KMID : 0525720200250030109
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Journal of Chitin and Chitosan
2020 Volume.25 No. 3 p.109 ~ p.116
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Loganin Content and Physiological Activities of Cornus officinalis Extracts Prepared with Different Methods
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Im So-Yeon
Jeong Kyoung-Ok
Lee Jeong-Ho
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Abstract
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The aim of this study was to investigate the potential of Cornus officinals as a content of protocatechuic acid and physiological activities. The analyzed the content of protocatechuic acid of Cornus officinals water extracts according to different extract temperature and time for extraction. It was analyzed as 7.68 ± 0.06 mg/g in the extract at 100℃ for 3 h. Protocatechuic acid content increased as extraction time and temperature increased. The activity of the Cornus officinals water extract at 100℃ for 3 h was measured. Antioxidant activity against the concentration of Cornus officinals water extract 1,000 μg/mL was measured. DPPH radical scavenging activity was measured at 53.58 ± 3.35%, ABTS radical scavenging activity at 18.22 ± 0.62%, and SOD activity at 69.6 ± 7.42%, antioxidant activity also increased as the processing concentration of extracts increased. Cell viability was shown for RAW 264.7 cells, and nitric oxide(NO) production was also inhibited. The α-Glucosidase inhibitory activity was determined to be 98.9 ± 4.45% at concentration of 1000 μg/mL. The nutritional components were analyzed to be 344.94 kcal/100g of calories, 80.83% of carbohydrates, 3.29% of crude protein, 0.94% of crude fat, and 347.61 mg/g of total sugars. Cornus officinals is thought to be developed as a functional food material because it contains protocatechuic acid and has antioxidant activity, anti-inflammatory and antidiabetic activity.
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KEYWORD
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Cornus officinalis, Loganin, Antioxidant, α-Glucosidase, Nitric oxide
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